Towards Antitumor Active trans ‐Platinum Compounds
نویسندگان
چکیده
منابع مشابه
Antitumor Trans Platinum Adducts of GMP and AMP
Recently it has been shown that several analogues of the clinically ineffective trans-DDP exhibit antitumor activity comparable to that of cis-DDP. The present paper describes the binding of antitumor trans-[PtCl(2)(E-iminoether)(2)] (trans-EE) to guanosinemonophosphate (GMP) and adenosinemonophosphate (AMP). We have used HPLC and (1)H and (15)N NMR to characterize the different adducts. In the...
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ژورنال
عنوان ژورنال: European Journal of Inorganic Chemistry
سال: 2009
ISSN: 1434-1948,1099-0682
DOI: 10.1002/ejic.200801118